The volume and distribution of fluids available in the gastrointestinal (GI) tract may substantially affect oral drug absorption.Magnetic resonance imaging (MRI) has been used in the past to quantify these fluid volumes in adults and its use is now being extended to the pediatric population.The present research pursued a Course a pied - Femme - Vet
Optimal designs for population pharmacokinetic studies of oral artesunate in patients with uncomplicated falciparum malaria
Abstract Background Currently, population pharmacokinetic (PK) studies of anti-malarial drugs are designed primarily by the logistical and ethical constraints of taking blood samples from patients, and the statistical models that are fitted to the data are not formally considered.This could lead to imprecise estimates of the target PK parameters, a
Who is dying from COVID-19 and when? An Analysis of fatalities in Tamil Nadu, India
Background: As the number of COVID-19 cases continues to rise, public health efforts must focus on preventing avoidable fatalities.Understanding the demographic and clinical characteristics of deceased COVID-19 patients; and estimation of time-interval between symptom onset, hospital admission and death could inform public health interventions focu
Comparison between measurements obtained with three different perineometers
OBJECTIVE: To Horn Speakers analyze the results obtained in the evaluation of intra-vaginal pressure using three different brands of perineometers in nulliparous volunteers.MATERIALS AND METHODS: Twenty nulliparous women with no anatomical alterations and/or dysfunction of the pelvic floor were enrolled in our study.All the women had the ability to